Aging is an inevitable consequence of our existence. However, since time immemorial, mankind has sought to overcome this process (and ideally, and completely gain immortality). We have not yet reached the ideal, but we can well increase life expectancy by a third thanks to the discovery of scientists from the United States.
A team of researchers from the National Institute of Aging in Bethesda has developed a drug that removes aging cells from the body. It turned out during the study of drugs called senolytics. These are experimental drugs that can selectively initiate the death of aged cells.
"Old cells tend to accumulate in the body, as a result of which the number of age-related diseases increases, and this, in turn, causes the death of new cells and aggravates the aging process."
In a series of experiments, 2 preparations of quercetin and dasatinib were given to a group of laboratory animals. It turned out that these drugs, both together and separately, increase life expectancy by an average of 30%. In addition, the mice showed improved cardiovascular function, increased endurance, and strengthened bone tissue. Intermittent administration of quercetin and dasatinib slowed the development of osteoporosis.
Now the researchers are aiming at a deeper study of the metabolism of the above-described drugs, but now we can say that in the near future there is no need to wait for the appearance of a "pill for old age", since quercetin and dasatinib have a lot of very unpleasant side effects, so the scientists face a very difficult task: Get rid of side effects while maintaining anti-aging properties.
Vladimir Kuznetsov