Scientists from the University of Western Australia have developed a substance based on several biological compounds that will prevent the formation of scars even with very deep wounds and cuts.
The development was based on the study of the mechanisms of work on the study of inhibitors of lysyl oxidase, as well as its enzymes. It's no secret that with minor injuries - scratches, abrasions and shallow cuts - the skin structure regenerates almost completely. This happens because these types of injuries do not damage the deep layers of the epidermis, for the restoration of which conventional healing mechanisms are not enough. The deep layers are rich in collagen fibers, for which lysyl oxidase and its enzymes are needed to "cross-link". These substances accelerate the wound healing process, during which, in a fairly short period of time, a strong, but not very aesthetic tissue with good protective properties is formed. Naturally, our cells do not "think" about the aesthetic side of the issue in an extreme situation for the organism.
But scientists from Australia thought about it: the author of the project, Swaminathan Yer, and his colleagues developed a substance based on an inhibitor, that is, a compound that blocks the activity of lysyl oxidase. Thus, when using an inhibitor at the stage of wound healing, instead of scar tissue, skin with a normal structure is formed, although it takes a little longer to heal. At the moment, the creators of the new compound are collaborating with Pharmaxis, conducting clinical trials and developing a unique drug. In vitro studies (roughly speaking, in vitro) on human fibroblasts have already been successfully carried out, and experiments on pigs and mice are planned in the near future. With a successful coincidence of circumstances, the creation of a new drug, which can become a new word in cosmetology, can take no more than 2-3 years.
VLADIMIR KUZNETSOV