Scientists at the University of Minnesota and the Mayo Clinic (USA) have found that the flavonoid fisetin, which is found in vegetables and fruits, slows down cellular aging and can prolong the life of the body. This was announced in a press release on MedicalXpress.
It is known that senescent cells, that is, aged cells that have stopped dividing and secrete pro-inflammatory substances, contribute to the deterioration of the surrounding tissues and the aging of the whole organism. As we age, the immune system, which helps to destroy these cells, becomes worse and worse, which leads to their accumulation.
Researchers have found that fisetin helps mice get rid of senescent cells, which improves rodents' health and lifespan. However, this is not about increasing the maximum possible life span, but about a significant reduction in the risk of senile diseases affecting longevity.
Earlier in September, it was reported that Mayo Clinic scientists had identified a link between defective cells and dementia. When the mechanisms promoting the death of senescent cells were activated, signs of inflammation disappeared, no accumulations of tau proteins were formed, and the brain mass remained within normal limits.